anti gdf11 primary antibody (R&D Systems)
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anti gdf11 primary antibody
Anti Gdf11 Primary Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 24 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/recombinant+gdf11/Recombinant+Human%2FMouse%2FRat+GDF-11%2FBMP-11+Protein/pm41637825-94-14-19
Average 93 stars, based on 24 article reviews
Anti Gdf11 Primary Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 24 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/recombinant+gdf11/Recombinant+Human%2FMouse%2FRat+GDF-11%2FBMP-11+Protein/pm41637825-94-14-19
Average 93 stars, based on 24 article reviews
anti gdf11 primary antibody - by Bioz Stars,
2026-09
93/100 stars
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Recombinant:Article Title: GDF11 alleviates secondary brain injury after intracerebral hemorrhage via attenuating mitochondrial dynamic abnormality and dysfunction Article Snippet: .. IP injections of Article Title: Hypoxia-induced miR-1260b regulates vascular smooth muscle cell proliferation by targeting GDF11 Article Snippet: Cell culture Human primary pulmonary artery smooth muscle cells (PASMCs) were purchased from Lonza (CC-2581) and cultured as previously described (11). .. For hypoxia, PASMCs in Sm-Gm2 medium (Lonza) were grown in a sealed modular incubator chamber (Billups-rothenberg Inc.) for 24 h at 37C after flushing with a mixture of 5% CO2, 1% O2 and 94% N2 for 4 min. For GDF11 stimulation, 10 ng of Article Title: Circulating α-Klotho Counteracts Transforming Growth Factor-β-Induced Sarcopenia. Article Snippet: From the Departments of Neurology,* Natural Sciences,z and Pathology,{ Kawasaki Medical School,zz Kurashiki; the Department of Health and Sports Science,y Faculty of Health Science and Technology, Kawasaki University of Medical Welfare, Kurashiki; the Department of Medical Science,x Teikyo University of Science, Tokyo; the Department of Animal and Marine Bioresource Sciences,k Graduate School of Agriculture, Kyushu University, Fukuoka; the Department of Food and Life Science,** School of Life and Environmental Science, Azabu University, Sagamihara; and the Research Coordination Group,yy Tokyo Research Park, R&D Division, Kyowa Kirin Co., Ltd., Tokyo, Japan Article Title: Growth Differentiation Factor 11 Evokes Lung Injury, Inflammation, and Fibrosis in Mice through the Activin A Receptor Type II-Like Kinase, 53kDa-Smad2/3 Signaling Pathway. Article Snippet: opyright a 2024 American Society for Inves echnologies. ttps://doi.org/10.1016/j.ajpath.2024.07.016 Growth differentiation factor 11 (GDF11) belongs to the transforming growth factor beta superfamily and participates in various pathophysiological processes.. Initially, GDF11 was suggested to act as a rejuvenator by improving age-related phenotypes of the heart, brain, and skeletal muscle in aged mice.. Recent studies demonstrate that GDF11 also serves as an adverse risk factor for human frailty and diseases. Article Title: Supraphysiological levels of GDF11 induce striated muscle atrophy. Article Snippet: .. At day 7 of differentiation, myotube cultures were separated into control (n = 5), 50 ng/ml recombinant Mstn (R&D Systems #788-G8; n = 4), 50 ng/ml Article Title: Supraphysiological levels of GDF 11 induce striated muscle atrophy Article Snippet: .. At day 7 of differentiation, myotube cultures were separated into control ( n = 5), 50 ng/ml recombinant Mstn (R&D Systems #788‐G8; n = 4), 50 ng/ml Article Title: Development of an ultra-sensitive Simoa assay to enable GDF11 detection: a comparison across bioanalytical platforms. Article Snippet: 2016 Background: Four bioanalytical platforms were evaluated to optimize sensitivity and enable detection of recombinant human GDF11 in biological matrices; ELISA, Meso Scale Discovery, Gyrolab xP Workstation and Simoa HD-1.. Results & methodology: After completion of custom assay development, the single-molecule ELISA (Simoa) achieved the greatest sensitivity with a lower limit of quantitation of 0.1 ng/ml, an improvement of 100-fold over the next sensitive platform (MSD).. Discussion & conclusion: This improvement was essential to enable detection of GDF11 in biological samples, and without the technology the sensitivity achieved on the other platforms would not have been sufficient. Article Title: Hypoxia-induced miR-1260b regulates vascular smooth muscle cell proliferation by targeting GDF11 Article Snippet: Human primary pulmonary artery smooth muscle cells (PASMCs) were purchased from Lonza (CC-2581) and cultured as previously described (11). .. For hypoxia, PASMCs in Sm-Gm2 medium (Lonza) were grown in a sealed modular incubator chamber (Billups-rothenberg Inc.) for 24 h at 37oC after flushing with a mixture of 5% CO2, 1% O2 and 94% N2 for 4 min. For GDF11 stimulation, 10 ng of Modification:Article Title: Circulating α-Klotho Counteracts Transforming Growth Factor-β-Induced Sarcopenia. Article Snippet: From the Departments of Neurology,* Natural Sciences,z and Pathology,{ Kawasaki Medical School,zz Kurashiki; the Department of Health and Sports Science,y Faculty of Health Science and Technology, Kawasaki University of Medical Welfare, Kurashiki; the Department of Medical Science,x Teikyo University of Science, Tokyo; the Department of Animal and Marine Bioresource Sciences,k Graduate School of Agriculture, Kyushu University, Fukuoka; the Department of Food and Life Science,** School of Life and Environmental Science, Azabu University, Sagamihara; and the Research Coordination Group,yy Tokyo Research Park, R&D Division, Kyowa Kirin Co., Ltd., Tokyo, Japan Control:Article Title: Growth Differentiation Factor 11 Evokes Lung Injury, Inflammation, and Fibrosis in Mice through the Activin A Receptor Type II-Like Kinase, 53kDa-Smad2/3 Signaling Pathway. Article Snippet: opyright a 2024 American Society for Inves echnologies. ttps://doi.org/10.1016/j.ajpath.2024.07.016 Growth differentiation factor 11 (GDF11) belongs to the transforming growth factor beta superfamily and participates in various pathophysiological processes.. Initially, GDF11 was suggested to act as a rejuvenator by improving age-related phenotypes of the heart, brain, and skeletal muscle in aged mice.. Recent studies demonstrate that GDF11 also serves as an adverse risk factor for human frailty and diseases. Article Title: Supraphysiological levels of GDF11 induce striated muscle atrophy. Article Snippet: .. At day 7 of differentiation, myotube cultures were separated into control (n = 5), 50 ng/ml recombinant Mstn (R&D Systems #788-G8; n = 4), 50 ng/ml Article Title: Supraphysiological levels of GDF 11 induce striated muscle atrophy Article Snippet: .. At day 7 of differentiation, myotube cultures were separated into control ( n = 5), 50 ng/ml recombinant Mstn (R&D Systems #788‐G8; n = 4), 50 ng/ml Saline:Article Title: Growth Differentiation Factor 11 Evokes Lung Injury, Inflammation, and Fibrosis in Mice through the Activin A Receptor Type II-Like Kinase, 53kDa-Smad2/3 Signaling Pathway. Article Snippet: opyright a 2024 American Society for Inves echnologies. ttps://doi.org/10.1016/j.ajpath.2024.07.016 Growth differentiation factor 11 (GDF11) belongs to the transforming growth factor beta superfamily and participates in various pathophysiological processes.. Initially, GDF11 was suggested to act as a rejuvenator by improving age-related phenotypes of the heart, brain, and skeletal muscle in aged mice.. Recent studies demonstrate that GDF11 also serves as an adverse risk factor for human frailty and diseases. Binding Assay:Article Title: Development of an ultra-sensitive Simoa assay to enable GDF11 detection: a comparison across bioanalytical platforms. Article Snippet: 2016 Background: Four bioanalytical platforms were evaluated to optimize sensitivity and enable detection of recombinant human GDF11 in biological matrices; ELISA, Meso Scale Discovery, Gyrolab xP Workstation and Simoa HD-1.. Results & methodology: After completion of custom assay development, the single-molecule ELISA (Simoa) achieved the greatest sensitivity with a lower limit of quantitation of 0.1 ng/ml, an improvement of 100-fold over the next sensitive platform (MSD).. Discussion & conclusion: This improvement was essential to enable detection of GDF11 in biological samples, and without the technology the sensitivity achieved on the other platforms would not have been sufficient. |
